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25 June 2012
Diabetic Peripheral Neuropathy linked to sleep apnoea in diabetes
Diabetes patients are more likely to experience obstructive sleep apnoea if they also have diabetic peripheral neuropathy, according to a Birmingham University study.
Researchers assessed 234 patients with type 2 diabetes and found OSA was independently associated with diabetic peripheral neuropathy. Overall prevalence of apnoea was 65%.
They found 60% of patients with OSA had neuropathy, compared to 27% of patients without OSA.
OSA is known to be associated with inflammation and oxidative stress, so we hypothesized that it would be associated with peripheral neuropathy in patients with T2DM, said lead author Abd Tahrani, clinical lecturer in endocrinology and diabetes at the University of Birmingham.
This is the first report to identify an independent association between OSA and DPN in these patients.
The study was published online in the American Journal of Respiratory and Critical Care Medicine.